High bone density in woman with mastocytosis

Diffuse increase in bone density L1-L4 with Z-score of 5.2

Increase in bone density at the left total hip with Z-score of 3.2

Case Description:

42 y old woman with longstanding mastocytosis, comorbidity of papillary thyroid Cancer (pT3,pN1b,Mx). Patient has presented with skin rash and flushing in 2014. Work up revealed elevated tryptase up to 132 mcg/l , c-kit in blood draw was positive, bone marrow biopsy was done, which showed a few mast cells, but no malignant-appearing mast cells.

Credit:

Susanne Trost MD
Clinical Densitometrist
Endocrinology, Diabetes and Metabolism
Assistant Professor
University of Minnesota, Twin Cities

References:

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